β-NAD

β-NAD: Premium Grade β-Nicotinamide Adenine Dinucleotide for Nutraceutical & Research Applications

Hunan Clover Origins Biotech Co., Ltd. provides premium β-Nicotinamide Adenine Dinucleotide with a purity of 99% by modern biosynthesis technology. Our β-NAD (CAS No. 53-84-9) is produced in ISO 9001, HACCP, FSSC 22000, Kosher and Halal certified plants with annual capacity of more than 5,000 tons.

Each batch is strictly tested by HPLC to assure purity of more than 98%, moisture content less than 5%, and heavy metals less than 10ppm. With over 25 years' experience in the sector, we can keep stock on hand for 1-2 day shipment, with reasonable prices and flexible MOQ for your business.

Whether you are manufacturing lifespan supplements, cellular energy formulations or diagnostic enzyme assays, our quality-regulated product offers the biological activity and stability your applications demand.

Product Specifications

Why Our β-NAD Stands Out?

Biosynthesis Technology of Superior Purity

α-NAD isomer impurity is typically introduced during conventional chemical synthesis and it works as a competitive inhibitor in biological systems. Our enzyme-catalyzed technique for biosynthesis keeps the α-NAD contamination <0.5% and the β-isomer always >99.5% pure.

This stereochemical accuracy is directly translated into enhanced enzymatic activity. Your formulations have uniform bioavailability and predictable absorption into the cell.

Pharma Quality Control

All production batches are tested using strict testing techniques. We validate D-ribose stereochemistry by measuring specific rotation. We ensure heavy metal compliance with ICP-MS testing and confirm microbiological safety through USP microbial limit tests.

Our functional enzymatic activity experiment with alcohol dehydrogenase (ADH) highlights the connection between chemical purity and biological catalytic effectiveness. What you will get is not only a pure powder, but a biologically active coenzyme, ready for your applications.

Moisture Control in Manufacturing & Packaging

The main enemy of the stability of NAD is its hygroscopicity. Too much moisture results in hydrolysis of the pyrophosphate bond, ruining your ingredient before it ever reaches your production line.

We maintain tight environmental controls throughout our manufacturing processes. Our facilities are stored in a humidity-controlled environment. Each batch is packed under a nitrogen atmosphere or vacuum seal. The moisture control helps to retain the enzymatic activity during storage and transit.

Core Benefits & Mechanisms

Supports Cellular Energy Metabolism

This product is the key coenzyme in routes of cellular respiration. It works as an electron transporter in oxidation-reduction processes in mitochondria. Your formulas enable the synthesis of ATP, the energy currency of every cell.

This makes our substance a great fit for energy-focused supplements for active adults, athletes and older populations undergoing natural metabolic decline.

Redox Cofactor Function

The redox pair NAD+/NADH participates in >500 enzymatic activities. This co-enzyme duo is the key to metabolic equilibrium, from glycolysis to the citric acid cycle, and from fatty acid oxidation to amino acid metabolism.

Your products assist normal cellular metabolism, which is supported by basic biochemistry.

Activation of Longevity Pathway

β-NAD is the crucial substrate for Sirtuin family proteins (SIRT1-7), which are enzymes that are directly involved in longevity studies. It stimulates PARPs involved in DNA repair and maintains calcium signaling via cADPR synthases.

These mechanisms put your formulations on the cutting edge of healthy aging science and anti-aging supplement markets.

DNA Repair & Cellular Maintenance

Cellular repair processes are stimulated by NAD+ using enzymes. PARPs sense DNA damage and respond . Sufficient pools of NAD+ are required for genomic integrity and tolerance to cellular stress.

This perk appeals to health-conscious individuals looking for proactive health and wellness solutions.

Target Applications

Anti-Aging & Longevity Formulas

The longevity supplement market is rapidly expanding. Consumers are increasingly searching for NAD+ precursors and direct NAD+ formulations. Our high-purity product places your brand in this premium space.

Combine with resveratrol, pterostilbene, or NMN for synergistic longevity formulations that will appeal to biohacking and wellness communities.

Cellular Energy and Mitochondrial Support

Energy decline is common among athletes, professionals and aging individuals. Product-centric formulations fight fatigue at the cellular level, providing basic metabolic support without stimulants.

Your goods can zero in on fitness recovery, mental clarity, and prolonged energy without the crash associated with caffeine-based solutions.

Clinical Diagnostics & Research Reagents

Lab and diagnostic firms use NAD+ to make their enzymatic assay kits to measure LDH, ALT, AST and other biomarkers. Pharmaceutical grade purity provides precision in high throughput clinical settings.

Validated diagnostic processes require certificates of analysis for each batch and consistent quality between batches and orders.

Functional Nutrition & Sports Performance

Professional sports nutrition uses substances with known mechanisms. The product supports mitochondrial function, redox balance and metabolic efficiency – the foundations of athletic performance.

Develop capsules, powders or liquid injections for the serious athlete and performance oriented consumer.

Industrial Biotech & Biocatalytic Synthesis

NAD+ is used as a cofactor of oxidoreductases for the manufacture of chiral intermediates by biotechnology businesses. Our ingredient is stable to mechanical shear and temperature variations in large-scale bioreactors.

Technical parameters fulfill the high criteria of industrial bioprocessing applications.

Quality Assurance You Can Trust

Testing Procedures in Depth

We don't just test for purity. Our quality control system assesses the whole impurity profile by HPLC, which detects degradation products such as nicotinamide and residual α-NAD isomer. Hydrolysis-caused degradation is prevented using Karl Fischer moisture analysis.

Verified by independent third parties Eurofins, SGS and Alkemist Labs. You get full transparency with each shipment.

Global Regulations Compliance

Our quality parameters are as good as or better than those of China, the European Union and the United States. FDA registration, FSSC 22000 certification, and Kosher/Halal approval open up markets in these regions.

If you are developing for domestic or foreign distribution, our compliance profile will assist in your regulatory journey.

Total Traceability System

Each stage of the production process from raw material to final packaging is accompanied by documentation. Batch-specific records ensure full traceability. If there is a problem several months after delivery, we can recreate the whole manufacturing history.

That kind of traceability is critical for supplement brands facing increased scrutiny from regulators and consumers demanding transparency.

FAQ

Q: How is the product different from β-NADH in formulations?

A: The product is the oxidized form that accepts electrons in metabolic reactions, while the product is the reduced form that donates electrons. For longevity and energy supplements, the product is preferred as it directly replenishes cellular NAD+ pools. NADH is typically used in different application contexts focused on immediate energy donation.

Q: How should the product be stored for stability?

A: Store in a dry, dark environment at 2-8°C for short-term use (up to 6 months) or -20°C for long-term stability (up to 24 months). Moisture is the primary cause of deterioration. Use containers purged with vacuum or nitrogen. Keep air exposure to a minimum and reseal immediately after opening.

Q: Is your product free of α-isomer contamination?

A: Yes. In our biosynthetic method, α-NAD is kept at less than 0.5% . The α-isomer is physiologically inactive and acts as a competitive inhibitor in enzymatic systems. This level of purity is important for the effectiveness of supplements and the accuracy of diagnostics.

Q: Is the product suitable for use in liquid formulations?

A: The product is stable in acidic aqueous solutions (pH 2.0-6.0) for short periods of time. Special buffer systems and stabilizers are needed to avoid hydrolysis into nicotinamide and ADP-ribose for long-term liquid shelf-life. We provide technical consulting services for liquid formulation development.

Q: Why is powder color sometimes inconsistent from batch to batch?

A: Generally white, but a slight off-white tint can occur from minimal moisture absorption or slight oxidation during handling. If HPLC purity is >98% , this has no effect on biological activity. Each COA certifies that purity is as specified, despite some color variance.

Q: What minimum order quantity do you require?

A: MOQ is variable according to your business size. We can supply stock items in quantities from 1kg upwards. Minimums may be higher based on production needs for custom specs. Talk to us about your specific needs.

Q: Do you provide samples for testing?

A: Yes . We offer free samples to eligible firms to test for quality, solubility and compatibility with your formulations. Sample development is done within 7 working days. Feel the quality . Request your sample .

Q: What documentation do you provide with shipments?

A: All our orders come with Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), specification document and certificates (ISO, HACCP, Kosher, Halal). For export orders, we supply commercial invoice, packing list and certificates of origin as required.

Partner With a Trusted Biotech Leader

Ready to elevate your formulations with premium β-NAD? Contact our team at info@cloverorigins.com to discuss specifications, request samples, or place your order today.