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L-Glutathione reduced Powder

Product Name: L-Glutathione reduced GSH Other name: GSH, L-Glutathione, Reduced Glutathione Certificate: FDA, ISO9001, HACCP Place of Origin: China Certificate: FDA, ISO9001, HACCP Stable Raw Material Supply Chain Complete Documentation Support

Description

Premium L-Glutathione Reduced Powder - High-Purity Bioactive Antioxidant Ingredient

Hunan Clover Origins Biotech offers you the best quality L-Glutathione Reduced Powder with remarkable 99% HPLC-tested purity. We are a reliable company with more than 25 years' experience in biotechnology and yearly production capacity of more than 5,000 tons. We sell this high performance tripeptide to the nutritional supplement, cosmeceutical and functional food industries globally. Our product is in accordance with worldwide standards including FDA registration, ISO 9001, HACCP, FSSC 22000, Kosher and Halal certificates. Our GSH powder has better stability and bioactivity for your formulations with a specific rotation of -15.5° to -17.5° and moisture content below 0.5%.

What Makes Our L-Glutathione Reduced Powder Different?

The product (GSH) is the physiologically active form of glutathione, a tripeptide comprising L-glutamic acid, L-cysteine and glycine. The functional sulfhydryl (-SH) group is the primary bioactive site of this substance and is responsible for the compound's high antioxidant effects.

The oxidized form ( GSSG ) just sits there. Reduced glutathione is actively giving up electrons to counteract reactive oxygen species ( ROS ). It is the gold standard choice for cellular detoxification and skin lightening treatments.

Our GSH powder is made by enzymatic fermentation with Saccharomyces cerevisiae. This biotechnological technique guarantees the L-configuration for best bioactivity. You obtain a uniform, high-purity ingredient that provides reliable outcomes in your formulations.

In fact, the characteristic mild whiff of sulfur is an indication of quality. It confirms the presence of active thiol groups. If you can't smell it, the material has usually oxidized and lost its power.

Technical Specifications & Quality Parameters

Parameter Specification
Assay (HPLC) ≥99.0%
Appearance White to off-white crystalline powder
CAS Number 70-18-8
Molecular Weight 307.32 g/mol
Molecular Formula C10H17N3O6S
Specific Rotation -15.5° to -17.5°
Moisture Content ≤0.5%
pH (aqueous solution) 3.0 to 4.0
Solubility Freely soluble in water
Heavy Metals <10 ppm
Test Method HPLC
Shelf Life 24 months (properly stored)

All batches are tested against USP43 and EP10 monographs. We verify assay content, specific rotation, and impurity profiles to ensure pharmaceutical and dietary supplement grades.

Core Benefits That Solve Industry Challenges

You face real challenges in formulation development. High oxidative stress in biological systems. Instability in sensitive formulations. The need for potent, endogenous intracellular antioxidants.

Our reduced glutathione powder addresses these pain points directly:

Antioxidant Defense Support - The active thiol group effectively neutralizes free radicals. This protects cells from oxidative damage and supports healthy aging.

Liver Detoxification Pathways - GSH is the primary hepatoprotectant. It binds to xenobiotics and facilitates their elimination through phase II conjugation reactions.

Cellular Redox Balance - Maintains the intracellular reducing environment necessary for proper protein folding and enzyme function.

Skin Brightening & Even Tone - Inhibits tyrosinase activity to reduce melanin synthesis. This makes it a popular ingredient in aesthetic medicine and cosmeceutical formulations.

Immune System Function - Supports lymphocyte proliferation and optimal immune response by maintaining cellular glutathione levels.

Primary Application Scenarios

Nutraceuticals and Food Supplements

Your clients want effective liver support and detox products. L-Glutathione Reduced Powder is the primary active ingredient for capsules, tablets and powder blends.

It is a major hepatoprotectant, detoxifying poisons and promoting phase II detoxification. Its excellent bioavailability when paired with suitable delivery mechanisms is liked by formulators.

Personal Care & Advanced Cosmeceuticals

GSH gives apparent results in high-end skin whitening serums and anti-aging lotions. It inhibits tyrosinase activity at cellular level while protecting skin cells against UV-induced oxidative damage.

The substance is used in esthetic medicine products where safety and efficacy are of crucial importance. Because it is endogenous, it is better tolerated and has less adverse effects than the synthetic forms.

Functional Foods & Drinks

Reduced glutathione acts as a clean-label antioxidant in complex liquid formulations, stabilizing vitamins and natural pigments and maintaining formulation integrity.

However, this application requires a precise buffering pH between 3.0 and 5.0. It keeps the reduced state in aqueous media and inhibits premature oxidation.

Storage & Stability Guidelines

Proper storage is critical to maintain potency and prevent degradation. GSH powder is hygroscopic and sensitive to environmental factors.

Storage Conditions:

  • Temperature: Below 25°C (preferably refrigerated)
  • Light: Store in dark containers or amber glass
  • Humidity: Keep in dry environment with desiccant
  • Atmosphere: Minimize exposure to air; use nitrogen flushing when possible

Stability Considerations:

The free thiol group is sensitive to alkaline pH (>7.0) and transition metals like iron and copper. Your formulations should be suitably buffered and should use chelating agents where indicated.

Yellowing indicates oxidation and exposure to moisture or UV light. This is clear evidence of the loss of biological activity in the degraded substance.

Why Partner With Clover Origins?

Trusted, Consistent Quality - Every batch is rigorously tested by 3rd party labs including Eurofins, SGS and Alkemist Labs. We offer complete traceability from raw materials to final products to ensure you receive consistent, reliable ingredients.

Flexible Production & Fast Delivery - With 3 contemporary manufacturing facilities and over 5,000 tons annual capacity, we keep stable inventory. Standard goods ship in 1-2 days . Custom specs 5-10 days.

Customization Services - We work with you to generate custom specs and compound compositions through our R&D team. We manufacture OEM/ODM for capsules, gummies, liquids, and powder mixtures.

Regulatory Compliance - Our quality system is compliant with norms in China, the European Union and the United States. This offers significant compliance benefits to customers serving highly regulated overseas markets.

Responsive Technical Support - Access technical documents in 12 hours. Sample development within 7 business days. Our staff offers competent guidance while you create your product.

Manufacturing base

FAQ

Q: Why does the reduced Glutathione Powder smell of sulfur?

A: The odor is a natural consequence of the presence of the active sulfhydryl (-SH) group that contains sulfur. Loss of scent usually means potency is gone or the item has deteriorated. This smell is actually a confirmation of the ingredient's bioactivity.

Q: How to preserve Glutathione Powder Reduced so that it doesn't get yellow?

A: It should be stored cool (<25°C), covered from light, and kept in a dry place with low humidity. Yellowing means oxidization from exposure to moisture or UV rays. For optimal results use amber glass containers and desiccants.

Q: What is the difference between Glutathione Powder Reduced and GSSG?

A: Reduced glutathione (GSH) is the "active" form of the antioxidant that transfers electrons to destroy free radicals. GSSG is the "spent" oxidized form that is produced after GSH has done its work of antioxidant activity. Only the reduced form provides the biological advantages required for formulations.

Q: Is your Glutathione Powder Reduced fermented or man-made?

A: Our quality product is made by enzymatic fermentation of yeast (Saccharomyces cerevisiae). This biotechnological procedure guarantees the maintenance of the L-configuration for optimal bioactivity, which is preferable to chemical synthesis methods.

Q: Is it compliant with USP43/EP10?

A: Yes. Every one of our premium batches is evaluated against USP and EP monographs for assay content, specific rotation and impurity profile to meet the international pharmaceutical and dietary supplement grades. Full documentation available upon request.

Q: What are your Minimum Order Quantities?

A: We offer flexible MOQ to accommodate both small-scale formulators and large-scale manufacturers. Let us know your volume needs and we will give you a quote tailored to you. Please contact our staff.

Q: Do you have any samples for me to test?

A: Yes. We give free samples for the approved consumers. Development of samples is accomplished in 7 working days. It allows you to test quality and performance before you place larger orders.

Lab

Certificaates

Contact Us for Premium L-Glutathione Reduced Powder

Ready to source pharmaceutical-grade L-Glutathione reduced Powder for your formulations? Email us at info@cloverorigins.com and experience the Clover Origins difference.

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