L-Glutathione oxidized Powder

L-Glutathione Oxidized Powder: Premium Grade GSSG for Research & Industrial Applications

We provide pharmaceutical-grade GSSG with 98% purity verified to ISO 9001, HACCP and FDA registration standards, with over 25 years' experience in the biotechnology ingredients industry.

Our L-Glutathione oxidized Powder is significantly more stable than reduced glutathione, and will retain its molecular integrity even under difficult processing conditions. We do batch-specific HPLC testing, heavy metal screening and microbiological analysis to assure consistent quality. With an annual production capacity of over 5,000 tons across three state-of-the-art manufacturing facilities, we meet your needs for laboratory grade materials for redox research or stable constituents for nutraceutical and cosmeceutical formulations. Our GSSG satisfies USP/EP monograph standards and ships from stock in 1-2 days.

What Is L-Glutathione Oxidized Powder?

This product is often referred to as GSSG and is the disulfide linked form of two reduced glutathione (GSH) molecules that give up electrons under oxidative stress. This ubiquitous tripeptide is an important biological redox indicator.

GSSG solves one of the major formulation challenges from an industrial perspective. Reduced glutathione is unstable in aqueous solution and at high temperatures and decomposes fast. Our oxidized version is a shelf-stable option that retains molecular integrity throughout production and storage.

GSSG is utilized by formulators to set well-defined redox potentials in advanced biological products. This prevents oxidative destruction of the other active substances, hence improving efficacy and extending the shelf life.

Technical Specifications & Properties

Our product meets stringent pharmaceutical-grade standards with the following technical parameters:

The powder is more stable as compared to GSH. It does not oxidize quickly in normal air, therefore it is useful in mixtures that have to last a long time. It is highly soluble and can be easily incorporated into aqueous systems, emulsions, and cell culture mediums.

Key Advantages & Industry Benefits

Improved Stability for Challenging Formulations

GSSG is chemically stable under harsh conditions whereas reduced glutathione is rapidly degraded and browns. Here is why it is the best option for:

• High-temperature processing applications
• Acidic pH formulations
• Long shelf-life products requiring consistent potency

Reliable Redox System Component

GSSG functions as a stable substrate within the glutathione-peroxidase cycle. It partners with glutathione reductase to regulate cellular redox balance, making it invaluable for:

• Oxidative stress research
• Aging and metabolic studies
• Liver function investigations

High Research & Analytical Value

The GSH/GSSG ratio serves as a gold-standard biomarker for cellular oxidative status. Researchers worldwide use our L-Glutathione oxidized Powder for:

• Apoptosis and signal transduction studies
• Cell culture media optimization
• Pharmaceutical oxidative damage models
• Laboratory analytical standards

Primary Application Areas

Research in Biochemistry and Cell Biology

Scientists use GSSG to tightly control redox conditions in bioreactors and cell culture systems. It protects cells from oxidative stress damage, while permitting precise determination of GSH/GSSG ratio in tests.

Dietary Supplements & Nutraceuticals Advanced

Our materials are used in formulators' products for liver health and detoxification. GSSG performs better in the acidic stomach environment than some unstable reduced forms, delivering glutathione precursors where they are required most.

Cosmeceuticals & Dermatological Products

GSSG is prized by the cosmetic industry for skin-whitening and anti-aging serums. Its durability in complex aqueous emulsion enables it to block tyrosinase activity, without the fast change of color associated with GSH degradation. This guarantees consistency in product esthetics and performance.

Pharmaceutical Clinical Trials & R&D

GSSG is an important reagent for oxidative stress models for drug developers. It allows investigators to explore metabolic pathways, mechanisms of pharmacological action and therapeutic therapies associated with redox imbalance.

Quality Assurance & Manufacturing Excellence

Every batch of our product undergoes comprehensive testing before release:

Quality Control Protocol:

• Active ingredient content verification (HPLC)
• Heavy metals analysis (Pb, As, Cd, Hg)
• Microbiological testing (TPC, yeast, mold, pathogens)
• Pesticide residue screening
• Solvent residue analysis
• Ethylene Oxide (EO) testing

Certifications & Compliance:

• FDA Registration
• ISO 9001
• FSSC 22000
• HACCP
• Kosher & Halal certified
• Meets EU, US, and Chinese quality standards

Third Party Verification:

We cooperate with globally recognized laboratories, like Eurofins, SGS, Alkemist Labs and NSF, to provide independent verification of quality claims.

With full batch traceability from raw material to final product, you can always count on consistent, reliable material.

FAQ

Q: What is the difference between oxidized glutathione and reduced glutathione?

A: The oxidized form (GSSG) is composed of two glutathione molecules joined by a disulfide bond, and the reduced form (GSH) has a free thiol group. GSSG has much better stability in formulations but needs to be converted back enzymatically to GSH in the body to have antioxidant benefits.

Q: What is the minimum order quantity?

A: For research grade applications, we may offer flexible MOQ from 1kg. The more you buy, the more you save with our volume price.

Q: Do you supply samples for testing?

A: Yes. We supply free samples (5-20g) for qualified research & commercial evaluation. Sample development is done in 7 working days.

Q: How do you maintain consistent quality throughout batches?

A: All production lots are tested with the same techniques and requirements are documented. We keep complete batch records and send out a Certificate of Analysis (CoA) with every shipment. Our quality management system (accredited according to ISO) ensures reproducibility.

Q: Do you give any regulatory compliance documentation?

A: We provide comprehensive technical packages including CoA, MSDS, specification sheets, allergen statements, BSE/TSE declarations, GMO status and country-of-origin certificates. Additional documentation is available upon request.

Q: What is the typical shelf life and storage requirement?

A: When stored properly in sealed containers away from light and moisture at 2-8°C, our GSSG maintains ≥98% purity for 24 months from the manufacturing date.

Partner With Clover Origins Today

Ready to secure a stable supply of pharmaceutical-grade L-Glutathione oxidized Powder for your formulations or research projects? Contact us today at info@cloverorigins.com to request your free sample.