Gentiopicroside Powder

Premium Gentiopicroside Powder - 98% HPLC Standardized Botanical Extract

unan Clover Origins Biotech Co., Ltd. provides high purity Gentiopicroside Powder standardized to 98% by HPLC, derived from the root of Gentiana scabra Bunge by approved ethanol-water extraction technique. Backed by more than 25 years of knowledge in botanical extract manufacturing and supported by an annual production capacity of over 5,000 tons, we provide pharmaceutical-grade secoiridoid glycoside that meets the primary industry requirements for dependable hepatoprotective and digestive wellness products. CAS 20831-76-9 Our product features outstanding thermal stability, precise molecular weight of 356.32 g/mol and full compliance with FDA, ISO 9001, HACCP, Kosher and Halal certificates. It gives manufacturers a reliable bioactive compound for advanced nutraceutical and functional health applications.

This crystalline powder (white to off-white) helps address batch to batch variability issues typical to raw gentian root materials. You get formulation accuracy for digestive bitters, liver support supplements and metabolic wellness products.

What Makes Our Gentiopicroside Powder Superior?

Our product is the gold standard for gentian bioactives in the global pharmaceutical and nutraceutical industries. Unlike crude botanical powders with variable potency, we provide a 98% standardized extract with micro-molar bioactivity levels required for hepatoprotective and anti-inflammatory compositions.

This secoiridoid glycoside is extracted from high quality Gentiana scabra root by controlled ethanol-water extraction. This process maintains the chiral purity and natural origin of the chemical while concentrating it to medicinal grade.

Your formulations give you reliable dosage response linearity. The powder remains intact when processed by normal wet granulation and tableting, provided the pH is neutral to slightly acidic.

Its genuine secoiridoid structure is shown by the chemical formula C16H20O9. Its high solubility in water, methanol and ethanol provides a wide range of formulation choices for capsules, tablets and liquid administration systems.

Technical Specifications & Quality Parameters

Our quality control laboratory validates every batch through third-party testing with Eurofins, SGS, and Alkemist Labs. You receive complete batch documentation including heavy metals, pesticide residues, microbiological analysis, and residual solvent testing.

Key Applications for B2B Formulators

Pharmaceutical Hepatoprotective Formulations

Gentiopicroside is used as an Active Pharmaceutical Ingredient (API) for acute jaundice hepatitis and chronic fibrosis liver protection medications. The chemical inhibits the activation of hepatic stellate cells and lowers inflammatory mediators like TNF-α, IL-6.

Prior to absorption, the compound resists stomach hydrolysis. This guarantees excellent bioavailability in complex biological environments.

Digestive Health Nutraceuticals

Gentiopicroside Powder is a strong agonist of the bitter taste receptor TAS2R. It activates the vagus nerve increasing the motility of the digestive tract and the release of enzymes in patients with hypochlorhydria.

Use it in premium digestive enzyme blends, Swedish Bitters capsules and appetite stimulant formulas. Strong bitter profile complies with traditional herbal wellness ideals, while satisfying modern standardization needs.

Metabolic & Liver Health Supplements

This bioactive is a favorite among formulators of botanical metabolic support systems and liver detox blends. Its antioxidant activity fights oxidative stress and contributes to maintaining healthy liver enzyme levels.

Its uniform potency makes it easy to dose in multi-ingredient liver support regimens. You deliver consistent therapeutic results from batch to batch.

Innovations in Dermocosmetic & Skincare

Gentiopicroside is used in advanced formulations for soothing serums and reactive skin lotions. It inhibits Nitric Oxide (NO) production in macrophages and is hence ideal for formulations targeting redness and inflammation.

The anti-inflammatory processes of your dermocosmetic solutions are clinically proven and have no synthetic counterpart.

Manufacturing Excellence & Production Capabilities

Clover Origins has three sophisticated manufacturing facilities with output capacity of more than 5,000 tons annually. Our combined manufacturing system ensures reliable supply chains and flexible minimum order quantities customized to your business needs.

We dispatch standard products from our available inventory in 1-2 days. We can provide full technical help during development and produce custom specs in only 5-10 days.

We have developed a method of extraction that is stable in solution up to 60°C. This protects the integrity of the secoiridoids through the concentration and drying processes to ensure that your finished products have optimum biological activity.

We reply to technical questions within 1 hour and supply analytical documents within 12 hours. Sample development for custom formulation projects is done within 7 working days.

Quality Assurance & Global Compliance

Our comprehensive quality management system holds FDA Registration, ISO 9001, FSSC 22000, HACCP, SC, Kosher, and Halal certifications. Every production batch undergoes full traceability from raw material sourcing through final packaging.

Testing & Verification

• Active Content: ≥98.0% Gentiopicroside by HPLC
• Heavy Metals: Compliant with EU, USP, and Chinese Pharmacopoeia standards
• Pesticide Residues: Multi-residue screening via GC-MS/MS and LC-MS/MS
• Microbiological: Total plate count, yeast/mold, E.coli, Salmonella testing
• Residual Solvents: Ethanol and water levels verified per ICH Q3C guidelines
• Ethylene Oxide: Non-detectable
• Benzo[a]pyrene: Below detection limits

Third-party verification through Eurofins, SGS, Alkemist Labs, and NSF provides independent confirmation of our quality claims. You receive COA documentation with every shipment for regulatory compliance in your target markets.

FAQ

Q: How much of a digestive health supplement should I take?

A: Digestive formulas typically contain 20-50mg 98% Gentiopicroside per serving. Final dose depends on your target market laws and formula synergy with other constituents.

Q: How stable is the product when tableted and encapsulated?

A: Our powder shows good thermal stability under normal tableting and wet granulation procedure. Best stability: pH neutral to slightly acidic. Avoid extended exposure above 60°C in aqueous solution.

Q: Can you provide documentation for FDA GRAS status?

A: Gentian extract has been traditionally used in food and beverages. We supply complete documentation, including safety data, heavy metal testing, and microbiology tests, for your regulatory submissions. For particular GRAS question support, contact our technical team.

Q: What is your minimum order quantity for special specifications?

A: We are flexible from 25kg for customized projects MOQ. Standard 98% ships from stock with no minimums for initial sampling and trial manufacturing.

Q: Are you able to assist with formulation for combo products?

A: Yes, our R&D team offers a complete formulation consultancy which includes compatibility testing with other botanicals, stability studies and help for pilot scale trials. All customer projects are treated with utmost secrecy.

Q: What is Gentiopicroside compared to the crude powder of gentian root?

A: Our 98% standardized extract has a bioavailable concentration that is 15-20 times more than crude root powder (which is normally 5-7% gentiopicroside). This allows for accurate dosing, a smaller capsule size and removes the batch-to-batch inconsistency that is inherent with raw botanicals.

Q: What are the packaging alternatives available?

A: Standard packing is 25 kg in fiber drums with double food-grade PE bags. We also have lesser quantities of 1kg, 5kg, 10kg aluminum foil packs. Custom packaging solutions are available upon request.

Partner With a Trusted Botanical Extract Leader

Ready to elevate your digestive wellness or hepatoprotective formulations with pharmaceutical-grade Gentiopicroside Powder? Contact our technical team at info@cloverorigins.com for samples, specifications, and custom development support today.