Premium Fisetin Powder – Senolytic Flavonoid for Healthy Aging & Longevity Formulations

Hunan Clover Origins Biotech Co., Ltd. supplies quality Fisetin Powder, purified to 90%-98%, collected from the stems and leaves of Cotinus coggygria (Smoke Tree). With over 25 years of experience in botanical extracts, our products are manufactured in FDA registered, ISO 9001, HACCP, FSSC 22000, Kosher and Halal certified facilities with a manufacturing capacity of over 5,000 tons per year. We deal with the industry's pressing problems of low bioavailability, batch inconsistency and compliance complexity by providing stable, traceable, internationally compliant senolytic flavonoid solutions that meet the exacting requirements of worldwide nutritional supplement manufacturers, functional food developers and longevity-focused formulation scientists.

What Is Fisetin Powder?

It is a natural flavonol (3,3',4',7-tetrahydroxyflavone) and a family of polyphenol. Fisetin is present in trace quantities in strawberries and apples but commercial grade Fisetin is isolated from Smoke Tree using ethanol-water to produce continuous, high strength concentrations.

This is a potent senolytic that specifically targets and kills senescent "zombie" cells, without affecting healthy tissue. This makes it a key ingredient in sophisticated formulations for healthy aging, cognitive wellness, and longevity in the supplement market.

Unlike most other antioxidants, Fisetin is not just a simple antioxidant. It functions at the cell signaling level. It induces autophagy, affects the mTOR pathway and provides neuroprotection. These are the underlying causes of age-related deterioration, not just the symptoms.

Product Specifications & Parameters

Parameter	Specification
Product Name	Fisetin Powder
Other Names	Smoke Tree Extract, Rhus cotinus Extract, Natural Flavonol
Latin Name	Cotinus coggygria var. cinereus Engl.
Active Ingredient	Fisetin
Purity	90%–98%
Test Method	HPLC
Used Part	Stems & Leaves
Appearance	Yellow to light yellow fine powder
Extraction Method	Ethanol & Water
Place of Origin	China
Certifications	FDA, ISO 9001, HACCP, FSSC 22000, Kosher, Halal
Molecular Formula	C₁₅H₁₀O₆
CAS Number	528-48-3
Moisture Content	<5%
Particle Size	<80 mesh (typical)

Key Benefits & Functional Advantages

Senolytic Activity for Cell Rejuvenation

Fisetin preferentially promotes apoptosis in senescent cells , main to tissue regeneration and cellular turnover. This particular mechanism supports healthy growing old at the mobile degree.

Antioxidant & Anti-Inflammatory Support

Fisetin is a effective loose radical scavenger and allows fight oxidative strain and chronic infection (inflammaging). It protects mobile systems from harm and facilitates to preserve a wholesome metabolic stability.

Neuroprotection & Cognitive Wellness

Fisetin crosses the blood-brain barrier and benefits the brain through boosting neuronal survival, improving synaptic plasticity, and defensive in opposition to age-associated cognitive decline.

Metabolism and Cardiovascular Health

This substance modulates critical signaling pathways which include mTOR and facilitates to preserve metabolic flexibility, cardiovascular function and healthful lipid metabolism.

Longevity & Multiple Pathway Effectiveness

Fisetin is a multi-target molecule. It combines synergistically with resveratrol, quercetin, spermidine and NAD+ boosters in advanced lifespan stacks, making it excellent for premium wellness formulations.

Benefits of Fisetin

Ideal Applications & Target Markets

Our product can be integrated into a wide range of product categories:

Longevity & Healthy Aging Supplements – cellular resilience and life-extension capsules, tablets and powder blends

Senolytic-Focused Formulations – standalone or combo products designed to clear senescent cells

Cognitive Wellness & Nootropic Blends – Brain Health Supplements for Focus, Memory & Neuroprotection

Advanced Antioxidant Systems – Multi-Ingredient Antioxidant Formulas for Broad Spectrum Oxidative Defense

Premium Wellness & Active Aging Products – high-end functional foods, beverages, and nutraceuticals for health-conscious customers

Our team provides full technical support and flexible OEM/ODM manufacturing for anything from clean-label capsules to liposomal delivery methods to bespoke powder blends.

Why Choose Clover Origins Fisetin Powder?

Excellence in Manufacturing

We have three state-of-the-art facilities with an annual capacity of over 5,000 tons to deliver consistent quality at scale. We are FDA registered and our lines are ISO certified to ensure every batch is produced to worldwide standards.

High Purity & Stability

Our 90%-98% Fisetin Powder is HPLC tested and validated by third - party labs (Eurofins, SGS, Alkemist Labs). Low moisture content, regulated particle size, and rigorous heavy metal/pesticide screening ensure formulation stability and safety.

Flexibility & Customization

Looking for a certain purity, particle size, or bespoke blend? Our R&D team develops custom solutions including micronized powders, liposomal precursors, and compound formulations. Flexible MOQs and fast turnaround times. Standard goods ship in 1-2 days, custom orders ship in 5-10 days.

Complete Regulatory Compliance

Our quality system complies with China GB, EU and US standards. Full documentation support including CoA, TDS, allergen statements, BSE/TSE declarations and stability studies – making your regulatory filings and market entry easy.

Responsive Support Team

Our team provides hands-on assistance throughout your product lifecycle from sample development (within 7 working days) to technical documentation (within 12 hours). We reply to requests in 1 hour, and offer continuous formulation consultation.

Manufacturing base

FAQ

Q: What is the usual dose of Fisetin in dietary supplements?

A: Common dosages are between 100mg and 500mg per serving depending on the goals of the formulation. Higher dosages (up to 1,000 mg) are utilized in clinical longevity protocols. Always consult a formulation professional.

Q: How does Fisetin compare to Quercetin or Resveratrol?

A: They're all flavonoids, but Fisetin has been shown to have superior senolytic potency in several trials. It is often combined with Quercetin for synergistic senolytic actions and with Resveratrol for comprehensive anti-aging support.

Q: Does the product dissolve in water?

A: Fisetin is not soluble in water. For better bioavailability we recommend micronization, liposomal encapsulation or formulation with emulsifiers or cyclodextrins. Our R&D team can help you design delivery systems.

Q: What quality tests do you perform on each batch?

A: Each batch is tested for purity by HPLC, screened for heavy metals (Pb, As, Cd, Hg), tested for pesticide residues, microbiologically tested and tested for solvent residues. Third - party verification is available on request.

Q: Can samples be provided for testing?

A: Yes, we offer free samples for qualifying customers. Contact us with your project specifications and we'll ship within 7 working days.

Q: Do you offer OEM/ODM services for finished products?

A: Yes. We create capsules, tablets, gummies, liquids and powder blends on an OEM/ODM basis. All initiatives are subject to strict confidentiality agreements.

Q: What certifications does your product carry?

A: Our product is manufactured in FDA registered, ISO 9001, HACCP, FSSC 22000, Kosher and Halal certified facilities. We offer complete regulatory compliance paperwork for worldwide markets.

Q: How do you ensure batch-to-batch consistency?

A: Full-process traceability, consistent extraction techniques and real-time quality monitoring. Each batch is verified against reference standards for consistent purity, appearance and efficacy.

Lab

Certificaates

Contact Us

Want to add premium Fisetin Powder to your product line? Samples, estimates and technical consultation - contact us immediately at info@cloverorigins.com.